A lack of understanding and failure to control antibodies is still a major barrier to transplantation and remains front and center in mechanisms of acute and chronic graft loss.

This meeting will bring together the experts to tackle these challenges to transplantation. Diagnostic experts will talk about the latest in crossmatching and detection of antibodies before, during and after transplantation. Top clinical investigators will review their experience with early and late allo-antibodies, desensitization practices, and their approaches using IVIG, bortizimib and anti-C5 complement antibodies. Leading basic scientists will discuss what regulates antibodies and antibody injury - including plasma cell development and B regulatory cells, and regulation by other antibodies. Advancing our mechanistic understanding of what produces and maintains sensitization is the only way to evolve our current approaches to eliminate anti-donor antibodies and manage resistance to therapy.

The AST Fellows Symposium is the premier meeting for clinical fellows and residents, surgical fellows, research fellows, pharmacists, non-doctoral allied health professionals, and other trainees entering the exciting field of solid organ transplantation! The AST Fellows Symposium gives attendees the opportunity to participate in specialized scientific sessions and meet one-on-one with senior transplant specialists. Space is limited at this popular meeting, and a limited number of travel grants are available. This is a great opportunity to strengthen your transplantation knowledge and advance your career!

The following sessions have been recorded prior to the meeting to allow you to study the topic as presented. The recorded presentations will not be reviewed at the meeting, but will go into further detail at the meeting. You are requested to review the recorded presentations prior to the meeting in preparation to go into further detail at the meeting.

Objectives:
- Describe the indications for transplantation
- Describe the evaluation of transplant candidates
- Select deceased donor organs that can be safely transplanted