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L2.07 - Actuation-Navigation-Sensory Capability in Cancer-Fighting Nanorobotic Agents 
April 7, 2015   4:00pm - 4:15pm

Robotics can enhance the therapeutic efficacy in cancer therapy beyond what is possible with the manipulation of molecular structures alone which has been the main focus of the pharmaceutical industry. Such robotic enhancement could rely on the implementation of advanced functionalities in each agent designed to transport a therapeutic payload to specific tumor sites that would yield optimized effects. Such functionalities would include navigation capability towards the sites of treatment in order to avoid systemic circulation, self-actuation providing a propelling force sufficient to penetrate the tumor volume beyond the diffusion limits of larger drug molecules, and sensory capability to target regions such as the hypoxic zones that would lead to the best treatment outcomes. Although the field of biomimetics has given rise to new technologies inspired by biological solutions at the macro- and nano-scales, an artificial solution supporting such an embedded capability level is still far beyond present technological feasibility. But methods relying on biology can also be inspired by far-reaching technological concepts. It is shown how such �reverse-biomimetic� approach can be used to implement medical nanorobotic agents having functionalities only envisioned for future medical nanorobots and which are still far beyond present technological feasibility at such a scale.

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